Doctors warn Madonna’s age, high-octane lifestyle and grueling prep for world tour may have left her susceptible to killer bug that landed her in ICU

Madonna‘s grueling preparation for her epic 80-show world tour may have left her vulnerable to falling ill, doctors warned today after news broke that the 64-year-old icon was hospitalized with a ‘serious bacterial infection’.

The legendary hitmaker — whose chart-topping career has spanned four decades — is expected to make a ‘full recovery’ after being intubated in intensive care.

Details over the exact cause of the ‘Material Girl’ singer’s health scare have yet to be released by her family, who were left ‘preparing for the worst’.

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EXCLUSIVE: Doctors say Madonna looked ‘exhausted, slim and not herself’ in photos taken days before Queen of Pop, 64, nearly died from bacterial infection in ICU